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ALDOB Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant ALDOB.

  • E - ALDOB Antibody (monoclonal) (M01) AT1117a
    Detection limit for recombinant GST tagged ALDOB is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05062
Other Accession BC029399
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a kappa
Clone Names 3B3
Calculated MW 39473 Da
Additional Information
Gene ID 229
Other Names Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Target/Specificity ALDOB (AAH29399, 1 a.a. ~ 316 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsALDOB Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Fructose-1,6-bisphosphate aldolase (EC is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.


The biochemical basis of hereditary fructose intolerance. Bouteldja N, et al. J Inherit Metab Dis, 2010 Apr. PMID 20162364.Increased prevalence of mutant null alleles that cause hereditary fructose intolerance in the American population. Coffee EM, et al. J Inherit Metab Dis, 2010 Feb. PMID 20033295.Secreted protein acidic and rich in cysteine (SPARC) gene polymorphism association with hepatocellular carcinoma in Italian patients. Segat L, et al. J Gastroenterol Hepatol, 2009 Dec. PMID 19817957.Five mucosal transcripts of interest in ulcerative colitis identified by quantitative real-time PCR: a prospective study. Eriksson A, et al. BMC Gastroenterol, 2008 Aug 12. PMID 18700007.Hereditary fructose intolerance: frequency and spectrum mutations of the aldolase B gene in a large patients cohort from France--identification of eight new mutations. Davit-Spraul A, et al. Mol Genet Metab, 2008 Aug. PMID 18541450.

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$ 315.00
Cat# AT1117a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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