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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AMACR Antibody (monoclonal) (M02)   

AMACR Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full-length recombinant AMACR.

  • WB - AMACR Antibody (monoclonal) (M02) AT1128a
    AMACR monoclonal antibody (M02), clone 1D8. Western Blot analysis of AMACR expression in HepG2 ( Cat # L019V1 ).
  • E - AMACR Antibody (monoclonal) (M02) AT1128a
    Detection limit for recombinant GST tagged AMACR is 1 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UHK6
Other Accession BC009471
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 1D8
Calculated MW 42387 Da
Additional Information
Gene ID 23600
Other Names Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
Target/Specificity AMACR (AAH09471, 1 a.a. ~ 198 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsAMACR Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.


AMACR is associated with advanced pathologic risk factors in sporadic colorectal adenomas. Lakis S, et al. World J Gastroenterol, 2010 May 28. PMID 20503447.How useful is alpha-methylacyl-CoA racemase (AMACR) immunohistochemistry in the differential diagnosis of kidney cancers? Szponar A, et al. Histopathology, 2010 Jan. PMID 20102405.Genetic susceptibility to distinct bladder cancer subphenotypes. Guey LT, et al. Eur Urol, 2010 Feb. PMID 19692168.Expression of alpha-methylacyl-CoA racemase (P504S) in sebaceous neoplasms. Halsey MA, et al. J Cutan Pathol, 2010 Apr. PMID 19638170.PTEN identified as important risk factor of chronic obstructive pulmonary disease. Hosgood HD 3rd, et al. Respir Med, 2009 Dec. PMID 19625176.

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$ 315.00
Cat# AT1128a
(40 western blots)
Availability: 7-10 days
Bulk Size
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