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  • Accession
  • Catalog #

AMACR Antibody (monoclonal) (M02)Purified Mouse Monoclonal Antibody (Mab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AT1128a 100 ug 400 ul 7-10 days $ 315.00 Add to cart
  • Specification
  • Citiations : 0
  • Reviews
  • Protocols
  • Backgrounds

AMACR Antibody (monoclonal) (M02) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ9UHK6
ReactivityHuman
Concentration1 mg/ml
IsotypeIgG2b Kappa
Clone Names1D8
Calculated MW42387 Da

AMACR Antibody (monoclonal) (M02) - Additional info

Gene ID 23600
Other Names
RACEalpha-methylacyl-CoA racemase
Target/Specificity
AMACR (AAH09471, 1 a.a. ~ 199 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution
WB~~1:500~1000
Format
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
AMACR Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.

AMACR Antibody (monoclonal) (M02) - Related products

AP10110b: AMACR Antibody (C-term)

RI10266: AMACR predesign siRNA

BP10110b: AMACR Antibody (C-term) Blocking peptide

AT1128a: AMACR Antibody (monoclonal) (M02)

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.

REFERENCES

AMACR is associated with advanced pathologic risk factors in sporadic colorectal adenomas. Lakis S, et al. World J Gastroenterol, 2010 May 28. PMID 20503447.How useful is alpha-methylacyl-CoA racemase (AMACR) immunohistochemistry in the differential diagnosis of kidney cancers? Szponar A, et al. Histopathology, 2010 Jan. PMID 20102405.Genetic susceptibility to distinct bladder cancer subphenotypes. Guey LT, et al. Eur Urol, 2010 Feb. PMID 19692168.Expression of alpha-methylacyl-CoA racemase (P504S) in sebaceous neoplasms. Halsey MA, et al. J Cutan Pathol, 2010 Apr. PMID 19638170.PTEN identified as important risk factor of chronic obstructive pulmonary disease. Hosgood HD 3rd, et al. Respir Med, 2009 Dec. PMID 19625176.