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  • Accession
  • Catalog #

AMBP Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AT1129a 100 ug 400 ul 7-10 days $ 315.00 Add to cart
  • Specification
  • Citiations : 0
  • Reviews
  • Protocols
  • Backgrounds

AMBP Antibody (monoclonal) (M01) - Product info

ApplicationIF, WB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionP02760
ReactivityHuman
Concentration0.5 mg/ml
IsotypeIgG1 Kappa
Clone Names3F1
Calculated MW38999 Da

AMBP Antibody (monoclonal) (M01) - Additional info

Gene ID 259
Other Names
HCP, ITI, ITIL, UTIalpha-1-microglobulin/bikunin precursor
Target/Specificity
AMBP (AAH41593, 19 a.a. ~ 353 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution
WB~~1:500~1000
Format
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
AMBP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.

AMBP Antibody (monoclonal) (M01) - Related products

RI10267: AMBP predesign siRNA

DC07431: Human AMBP cDNA Clone

LY12281a: AMBP Over-expression Lysate

AT1129a: AMBP Antibody (monoclonal) (M01)

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

REFERENCES

Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Bikunin and alpha(1)-microglobulin/bikunin precursor (AMBP) gene mutational screening in patients with kidney stones: a case-control study. Igci M, et al. Scand J Urol Nephrol, 2010 Jul 5. PMID 20602574.Bikunin loss in urine as useful marker for bladder carcinoma. Tsui KH, et al. J Urol, 2010 Jan. PMID 19914646.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Increased levels of cell-free hemoglobin, oxidation markers, and the antioxidative heme scavenger alpha(1)-microglobulin in preeclampsia. Olsson MG, et al. Free Radic Biol Med, 2010 Jan 15. PMID 19879940.