ANXA2 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a full length recombinant ANXA2.
|Application ||WB, IF|
|Calculated MW||38604 Da|
|Other Names||Annexin A2, Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36, ANXA2, ANX2, ANX2L4, CAL1H, LPC2D|
|Target/Specificity||ANXA2 (AAH66955, 19 a.a. ~ 357 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||ANXA2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
1.The interaction with caveolae-associated proteins regulates enolase-1 subcellular localization.Zakrzewicz D, Didiasova M, Zakrzewicz A, Hocke AC, Uhle F, Markart P, Preissner KT, Wygrecka MBiochem J. 2014 Jun 1;460(2):295-307. doi: 10.1042/BJ20130945.2.Peripheral blood monocyte-expressed ANXA2 geneis involved in pathogenesis of osteoporosis in humans.Deng FY, Lei SF, Zhang Y, Zhang YL, Zheng YP, Zhang LS, Pan R, Wang L, Tian Q, Shen H, Zhao M, Lundberg YW, Liu YZ, Papasian CJ, Deng HW.Mol Cell Proteomics. 2011 Aug 4. [Epub ahead of print]3.Proteomic Analysis of Climatic Keratopathy Droplets.Menegay M, Lee D, Tabbara KF, Cafaro TA, Urrets-Zavalia JA, Serra HM, Bhattacharya SK.Invest Ophthalmol Vis Sci. 2008 Jul;49(7):2829-37. Epub 2008 Mar 31.
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