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AP4M1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant AP4M1.

  • WB - AP4M1 Antibody (monoclonal) (M01) AT1157a
    AP4M1 monoclonal antibody (M01), clone 2C4 Western Blot analysis of AP4M1 expression in HeLa ( Cat # L013V1 ).
  • E - AP4M1 Antibody (monoclonal) (M01) AT1157a
    Detection limit for recombinant GST tagged AP4M1 is 1 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00189
Other Accession NM_004722
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2C4
Calculated MW 49977 Da
Additional Information
Gene ID 9179
Other Names AP-4 complex subunit mu-1, AP-4 adaptor complex mu subunit, Adaptor-related protein complex 4 subunit mu-1, Mu subunit of AP-4, Mu-adaptin-related protein 2, mu-ARP2, Mu4-adaptin, mu4, AP4M1, MUARP2
Target/Specificity AP4M1 (NP_004713, 354 a.a. ~ 453 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsAP4M1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.


Mutation in the AP4M1 gene provides a model for neuroaxonal injury in cerebral palsy. Verkerk AJ, et al. Am J Hum Genet, 2009 Jul. PMID 19559397.Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4. Matsuda S, et al. Neuron, 2008 Mar 13. PMID 18341993.Subunit-specific regulation of NMDA receptor endocytosis. Lavezzari G, et al. J Neurosci, 2004 Jul 14. PMID 15254094.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.Adaptor protein complex-4 (AP-4) is expressed in the central nervous system neurons and interacts with glutamate receptor delta2. Yap CC, et al. Mol Cell Neurosci, 2003 Oct. PMID 14572453.

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$ 315.00
Cat# AT1157a
(40 western blots)
Availability: 7-10 days
Bulk Size
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