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ARHGAP6 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ARHGAP6.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O43182 |
| Other Accession | NM_013427 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 6B3 |
| Calculated MW | 105947 Da |
| Gene ID | 395 |
|---|---|
| Other Names | Rho GTPase-activating protein 6, Rho-type GTPase-activating protein 6, Rho-type GTPase-activating protein RhoGAPX-1, ARHGAP6, RHOGAP6 |
| Target/Specificity | ARHGAP6 (NP_038286, 531 a.a. ~ 636 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ARHGAP6 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
References
1.Genetic screening in C. Elegans identifies rho- GTPase activating protein 6 as novel HERG regulator.Potet F, Petersen CI, Boutaud O, Shuai W, Stepanovic SZ, Balser JR, Kupershmidt S.J Mol Cell Cardiol. 2009 Feb;46(2):257-67. Epub 2008 Nov 5.
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