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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ARRB2 Antibody (monoclonal) (M01)   

ARRB2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant ARRB2.

  • WB - ARRB2 Antibody (monoclonal) (M01) AT1201a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - ARRB2 Antibody (monoclonal) (M01) AT1201a
    Western Blot analysis of ARRB2 expression in transfected 293T cell line by ARRB2 monoclonal antibody (M01), clone 3G1.

    Lane 1: ARRB2 transfected lysate(46 KDa).
    Lane 2: Non-transfected lysate.
  • IF - ARRB2 Antibody (monoclonal) (M01) AT1201a
    Immunofluorescence of monoclonal antibody to ARRB2 on HeLa cell . [antibody concentration 10 ug/ml]
  • E - ARRB2 Antibody (monoclonal) (M01) AT1201a
    Detection limit for recombinant GST tagged ARRB2 is approximately 0.03ng/ml as a capture antibody.
  •  - ARRB2 Antibody (monoclonal) (M01) AT1201a
    Proximity Ligation Analysis of protein-protein interactions between MAPK3 and ARRB2. HeLa cells were stained with anti-MAPK3 rabbit purified polyclonal 1:1200 and anti-ARRB2 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32121
Other Accession BC007427
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3G1
Calculated MW 46106 Da
Additional Information
Gene ID 409
Other Names Beta-arrestin-2, Arrestin beta-2, ARRB2, ARB2, ARR2
Target/Specificity ARRB2 (AAH07427, 300 a.a. ~ 409 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsARRB2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.


beta-Arrestin2 influences the response to methadone in opioid-dependent patients. Oneda B, et al. Pharmacogenomics J, 2010 Jun 1. PMID 20514076.Beta-arrestin 2 regulates Toll-like receptor 4-mediated apoptotic signalling through glycogen synthase kinase-3beta. Li H, et al. Immunology, 2010 Aug. PMID 20497256.Preliminary evidence of ethnic divergence in associations of putative genetic variants for methamphetamine dependence. Bousman CA, et al. Psychiatry Res, 2010 Jul 30. PMID 20478633.Beta-arrestin 2 is required for B1 receptor-dependent post-translational activation of inducible nitric oxide synthase. Kuhr FK, et al. FASEB J, 2010 Jul. PMID 20228252.Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function. Shankar H, et al. J Biol Chem, 2010 Mar 12. PMID 20056609.

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$ 315.00
Cat# AT1201a
(40 western blots)
Availability: 7-10 days
Bulk Size
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