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ASPA Antibody (monoclonal) (M09)

Mouse monoclonal antibody raised against a partial recombinant ASPA.

  • WB - ASPA Antibody (monoclonal) (M09) AT1218a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • IF - ASPA Antibody (monoclonal) (M09) AT1218a
    Immunofluorescence of monoclonal antibody to ASPA on HeLa cell . [antibody concentration 10 ug/ml]
  • E - ASPA Antibody (monoclonal) (M09) AT1218a
    Detection limit for recombinant GST tagged ASPA is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P45381
Other Accession NM_000049
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 3C11
Calculated MW 35735 Da
Additional Information
Gene ID 443
Other Names Aspartoacylase, Aminoacylase-2, ACY-2, ASPA, ACY2, ASP
Target/Specificity ASPA (NP_000040, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsASPA Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene.


Human variation in alcohol response is influenced by variation in neuronal signaling genes. Joslyn G, et al. Alcohol Clin Exp Res, 2010 May. PMID 20201926.Examination of the mechanism of human brain aspartoacylase through the binding of an intermediate analogue. Le Coq J, et al. Biochemistry, 2008 Mar 18. PMID 18293939.Carrier frequency of autosomal-recessive disorders in the Ashkenazi Jewish population: should the rationale for mutation choice for screening be reevaluated? Fares F, et al. Prenat Diagn, 2008 Mar. PMID 18264947.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.Mutational analysis of aspartoacylase: implications for Canavan disease. Hershfield JR, et al. Brain Res, 2007 May 7. PMID 17391648.

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$ 315.00
Cat# AT1218a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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