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B3GNT1 Antibody (monoclonal) (M05)
Mouse monoclonal antibody raised against a partial recombinant B3GNT1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NY97 |
| Other Accession | NM_006577 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 1A8 |
| Calculated MW | 46022 Da |
| Gene ID | 10678 |
|---|---|
| Other Names | N-acetyllactosaminide beta-1, 3-N-acetylglucosaminyltransferase 2, Beta-1, 3-N-acetylglucosaminyltransferase 1, BGnT-1, Beta-1, 3-Gn-T1, Beta3Gn-T1, Beta-1, 3-galactosyltransferase 7, Beta-1, 3-GalTase 7, Beta3Gal-T7, Beta3GalT7, b3Gal-T7, Beta-3-Gx-T7, UDP-Gal:beta-GlcNAc beta-1, 3-galactosyltransferase 7, UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 2, BGnT-2, Beta-1, 3-Gn-T2, Beta-1, 3-N-acetylglucosaminyltransferase 2, Beta3Gn-T2, UDP-galactose:beta-N-acetylglucosamine beta-1, 3-galactosyltransferase 7, B3GNT2, B3GALT7, B3GNT1 |
| Target/Specificity | B3GNT1 (NP_006568, 111 a.a. ~ 210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | B3GNT1 Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains.
References
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Australo-Anglo-American Spondyloarthritis Consortium (TASC), et al. Nat Genet, 2010 Feb. PMID 20062062.Activation of beta1,3-N-acetylglucosaminyltransferase-2 (beta3Gn-T2) by beta3Gn-T8. Possible involvement of beta3Gn-T8 in increasing poly-N-acetyllactosamine chains in differentiated HL-60 cells. Seko A, et al. J Biol Chem, 2008 Nov 28. PMID 18826941.Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Liu T, et al. J Proteome Res, 2005 Nov-Dec. PMID 16335952.Characterization of a cDNA encoding a protein with limited similarity to beta1, 3-N-acetylglucosaminyltransferase. Zheng H, et al. Mol Biol Rep, 2004 Sep. PMID 15560372.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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