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BDKRB2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant BDKRB2.

     
  • WB - BDKRB2 Antibody (monoclonal) (M01) AT1289a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.34 KDa) .
    detail
  • E - BDKRB2 Antibody (monoclonal) (M01) AT1289a
    Detection limit for recombinant GST tagged BDKRB2 is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P30411
Other Accession NM_000623
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 lambda
Clone Names 3F6
Calculated MW 44461 Da
Additional Information
Gene ID 624
Other Names B2 bradykinin receptor, B2R, BK-2 receptor, BDKRB2, BKR2
Target/Specificity BDKRB2 (NP_000614, 1 a.a. ~ 60 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsBDKRB2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.

References

Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities. Docherty SJ, et al. BMC Genet, 2010 Jul 5. PMID 20602751.Interactions among related genes of renin-angiotensin system associated with type 2 diabetes. Yang JK, et al. Diabetes Care, 2010 Jun 30. PMID 20592051.No association between alleles of the bradykinin receptor-B2 gene and acute mountain sickness. Wang P, et al. Exp Biol Med (Maywood), 2010 Jun. PMID 20511677.Establishment of an in vivo model facilitates B2 receptor protein maturation and heterodimerization. Abd Alla J, et al. Integr Biol (Camb), 2010 Apr 7. PMID 20473401.

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$ 350.00
Cat# AT1289a
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