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BSCL2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant BSCL2.

  • WB - BSCL2 Antibody (monoclonal) (M01) AT1314a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • E - BSCL2 Antibody (monoclonal) (M01) AT1314a
    Detection limit for recombinant GST tagged BSCL2 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96G97
Other Accession NM_032667
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1G4
Calculated MW 44392 Da
Additional Information
Gene ID 26580
Other Names Seipin, Bernardinelli-Seip congenital lipodystrophy type 2 protein, BSCL2
Target/Specificity BSCL2 (NP_116056, 259 a.a. ~ 357 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsBSCL2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


Complementary mutations in seipin gene in a patient with Berardinelli-Seip congenital lipodystrophy and dystonia: phenotype variability suggests multiple roles of seipin gene. Wu YR, et al. J Neurol Neurosurg Psychiatry, 2009 Oct. PMID 19762912.The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation. Chen W, et al. Endocrinology, 2009 Oct. PMID 19574402.Two Japanese infants with congenital generalized lipodystrophy due to BSCL2 mutations. Nishiyama A, et al. Pediatr Int, 2009 Dec. PMID 19438831.A novel 16p locus associated with BSCL2 hereditary motor neuronopathy: a genetic modifier? Brusse E, et al. Neurogenetics, 2009 Oct. PMID 19396477.Clincial and pathological study of distal motor neuropathy with N88S mutation in BSCL2. Chen B, et al. Neuropathology, 2009 Oct. PMID 19323790.

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$ 315.00
Cat# AT1314a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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