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C1D Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a full length recombinant C1D.

     
  • IF - C1D Antibody (monoclonal) (M03) AT1333a
    Immunofluorescence of monoclonal antibody to C1D on HeLa cell. [antibody concentration 10 ug/ml]
    detail
  • WB - C1D Antibody (monoclonal) (M03) AT1333a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (41.25 KDa) .
    detail
  • WB - C1D Antibody (monoclonal) (M03) AT1333a
    C1D monoclonal antibody (M03), clone 6H2 Western Blot analysis of C1D expression in HeLa ( (Cat # AT1333a )
    detail
  • WB - C1D Antibody (monoclonal) (M03) AT1333a
    Western Blot analysis of C1D expression in transfected 293T cell line by C1D monoclonal antibody (M03), clone 6H2.

    Lane 1: C1D transfected lysate(16 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • IHC - C1D Antibody (monoclonal) (M03) AT1333a
    Immunoperoxidase of monoclonal antibody to C1D on formalin-fixed paraffin-embedded human colon. [antibody concentration 1 ug/ml]
    detail
  • E - C1D Antibody (monoclonal) (M03) AT1333a
    Detection limit for recombinant GST tagged C1D is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, E
Primary Accession Q13901
Other Accession BC005235
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 6H2
Calculated MW 16019 Da
Additional Information
Gene ID 10438
Other Names Nuclear nucleic acid-binding protein C1D, hC1D, C1D
Target/Specificity C1D (AAH05235, 1 a.a. ~ 141 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsC1D Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.

References

Polymorphisms in innate immunity genes and risk of childhood leukemia. Han S, et al. Hum Immunol, 2010 Jul. PMID 20438785.Risk of meningioma and common variation in genes related to innate immunity. Rajaraman P, et al. Cancer Epidemiol Biomarkers Prev, 2010 May. PMID 20406964.Common variation in genes related to innate immunity and risk of adult glioma. Rajaraman P, et al. Cancer Epidemiol Biomarkers Prev, 2009 May. PMID 19423540.C1D is a major autoantibody target in patients with the polymyositis-scleroderma overlap syndrome. Schilders G, et al. Arthritis Rheum, 2007 Jul. PMID 17599775.C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing. Schilders G, et al. Nucleic Acids Res, 2007. PMID 17412707.

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$ 350.00
Cat# AT1333a
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Availability: 7-10 days
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