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C3 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT1345a | 50 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
C3 Antibody (monoclonal) (M01) - Product info | |
| Application | WB
|
| Primary Accession | P01024 |
| Other Accession | NP_000055 |
| Reactivity | Human |
| Isotype | IgG2a Kappa |
| Clone Names | 5F9 |
| Calculated MW | 187148 Da |
C3 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 718 | |
| Other Names ASP, CPAMD1complement component 3 | |
| Target/Specificity C3 (NP_000055, 1534 a.a. ~ 1645 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions C3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
C3 Antibody (monoclonal) (M01) - Related products
C3 Antibody (monoclonal) (M01) - Application data
-
C3 monoclonal antibody (M01), clone 5F9 Western Blot analysis of C3 expression in A-431 ( Cat # L015V1 ).
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Immunoperoxidase of monoclonal antibody to C3 ( Cat # AT1345a ) on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]
C3 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.
REFERENCES
R102G polymorphism of the C3 gene associated with exudative age-related macular degeneration in a French population. Zerbib J, et al. Mol Vis, 2010 Jul 15. PMID 20664795. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624. Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism. Beckers MM, et al. Eur J Intern Med, 2010 Aug. PMID 20603037. Determination of a gene and environment risk model for age-related macular degeneration. Gibson J, et al. Br J Ophthalmol, 2010 Jun 24. PMID 20576771.
