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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CABC1 Antibody (monoclonal) (M05A)   

CABC1 Antibody (monoclonal) (M05A)

Mouse monoclonal antibody raised against a partial recombinant CABC1.

  • WB - CABC1 Antibody (monoclonal) (M05A) AT1362a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - CABC1 Antibody (monoclonal) (M05A) AT1362a
    CABC1 monoclonal antibody (M05A), clone 8F7 Western Blot analysis of CABC1 expression in Hela S3 NE ( (Cat # AT1362a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NI60
Other Accession BC005171
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgM Kappa
Clone Names 8F7
Calculated MW 71950 Da
Additional Information
Gene ID 56997
Other Names Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, 2711-, aarF domain-containing protein kinase 3, ADCK3, CABC1
Target/Specificity CABC1 (AAH05171, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCABC1 Antibody (monoclonal) (M05A) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.


ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Lagier-Tourenne C, et al. Am J Hum Genet, 2008 Mar. PMID 18319074.CABC1 gene mutations cause ubiquinone deficiency with cerebellar ataxia and seizures. Mollet J, et al. Am J Hum Genet, 2008 Mar. PMID 18319072.The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.

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$ 315.00
Cat# AT1362a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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