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CACNA1S Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CACNA1S.

  • E - CACNA1S Antibody (monoclonal) (M01) AT1365a
    Detection limit for recombinant GST tagged CACNA1S is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13698
Other Accession NM_000069
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2C5
Calculated MW 212350 Da
Additional Information
Gene ID 779
Other Names Voltage-dependent L-type calcium channel subunit alpha-1S, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Voltage-gated calcium channel subunit alpha Cav11, CACNA1S, CACH1, CACN1, CACNL1A3
Target/Specificity CACNA1S (NP_000060, 1743 a.a. ~ 1838 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCACNA1S Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility.


L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. Yokoyama K, et al. Nephron Clin Pract, 2010. PMID 20424473.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.The role of CACNA1S in predisposition to malignant hyperthermia. Carpenter D, et al. BMC Med Genet, 2009 Oct 13. PMID 19825159.Novel CACNA1S mutation causes autosomal dominant hypokalemic periodic paralysis in a South American family. Ke T, et al. J Hum Genet, 2009 Nov. PMID 19779499.Increasing the number of diagnostic mutations in malignant hyperthermia. Levano S, et al. Hum Mutat, 2009 Apr. PMID 19191329.

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$ 315.00
Cat# AT1365a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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