CD58 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant CD58.
|Application ||WB, IHC, IF, E|
|Calculated MW||28147 Da|
|Other Names||Lymphocyte function-associated antigen 3, Ag3, Surface glycoprotein LFA-3, CD58, CD58, LFA3|
|Target/Specificity||CD58 (AAH05930, 1 a.a. ~ 240 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||CD58 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.
Host genetic factors and vaccine-induced immunity to HBV infection: haplotype analysis. Ryckman KK, et al. PLoS One, 2010 Aug 18. PMID 20806065.Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients. Jensen CJ, et al. PLoS One, 2010 Apr 2. PMID 20368992.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Raychaudhuri S, et al. Nat Genet, 2009 Dec. PMID 19898481.Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score. De Jager PL, et al. Lancet Neurol, 2009 Dec. PMID 19879194.
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