CD7 Antibody (monoclonal) (M04)
Mouse monoclonal antibody raised against a full length recombinant CD7.
|Application ||WB, IP, E|
|Calculated MW||25409 Da|
|Other Names||T-cell antigen CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, CD7, CD7|
|Target/Specificity||CD7 (AAH09293, 21 a.a. ~ 240 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||CD7 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.
CD7 in acute myeloid leukemia: correlation with loss of wild-type CEBPA, consequence of epigenetic regulation. R?hrs S, et al. J Hematol Oncol, 2010 Apr 14. PMID 20398252.Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia. Rogers SL, et al. Mol Cancer, 2010 Feb 22. PMID 20175919.Frequent CD7 antigen loss in aggressive natural killer-cell leukemia: a useful diagnostic marker. Yoo EH, et al. Korean J Lab Med, 2009 Dec. PMID 20046078.Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells. Koh HS, et al. Mol Cells, 2009 Dec 31. PMID 19937140.Glycodelin A triggers T cell apoptosis through a novel calcium-independent galactose-binding lectin activity. SundarRaj S, et al. Mol Immunol, 2009 Oct. PMID 19683346.
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