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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CDC14A Antibody (monoclonal) (M02)   

CDC14A Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant CDC14A.

  • WB - CDC14A Antibody (monoclonal) (M02) AT1456a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - CDC14A Antibody (monoclonal) (M02) AT1456a
    Western Blot analysis of CDC14A expression in transfected 293T cell line by CDC14A monoclonal antibody (M02), clone 1F11.

    Lane 1: CDC14A transfected lysate(66.6 KDa).
    Lane 2: Non-transfected lysate.
  • IF - CDC14A Antibody (monoclonal) (M02) AT1456a
    Immunofluorescence of monoclonal antibody to CDC14A on HeLa cell. [antibody concentration 10 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UNH5
Other Accession NM_003672
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1F11
Calculated MW 66574 Da
Additional Information
Gene ID 8556
Other Names Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A, CDC14A
Target/Specificity CDC14A (NP_003663, 431 a.a. ~ 530 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCDC14A Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.


Centrosome-related genes, genetic variation, and risk of breast cancer. Olson JE, et al. Breast Cancer Res Treat, 2010 May 28. PMID 20508983.Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair. Mocciaro A, et al. J Cell Biol, 2010 May 17. PMID 20479464.Mutational analysis of mononucleotide repeats in dual specificity tyrosine phosphatase genes in gastric and colon carcinomas with microsatellite instability. Song SY, et al. APMIS, 2010 May. PMID 20477815.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Brap2 facilitates HsCdc14A Lys-63 linked ubiquitin modification. Chen JS, et al. Biotechnol Lett, 2009 May. PMID 19152073.

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$ 315.00
Cat# AT1456a
(40 western blots)
Availability: 7-10 days
Bulk Size
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