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CDKN2D Antibody (monoclonal) (M08)

Mouse monoclonal antibody raised against a full-length recombinant CDKN2D.

  • WB - CDKN2D Antibody (monoclonal) (M08) AT1483a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (44 KDa) .
  • WB - CDKN2D Antibody (monoclonal) (M08) AT1483a
    Western Blot analysis of CDKN2D expression in transfected 293T cell line by CDKN2D monoclonal antibody (M08), clone 2E10.

    Lane 1: CDKN2D transfected lysate(17.7 KDa).
    Lane 2: Non-transfected lysate.
  • IP - CDKN2D Antibody (monoclonal) (M08) AT1483a
    Immunoprecipitation of CDKN2D transfected lysate using anti-CDKN2D monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with CDKN2D MaxPab rabbit polyclonal antibody.
  • E - CDKN2D Antibody (monoclonal) (M08) AT1483a
    Detection limit for recombinant GST tagged CDKN2D is 0.1 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55273
Other Accession BC001822
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 2E11
Calculated MW 17700 Da
Additional Information
Gene ID 1032
Other Names Cyclin-dependent kinase 4 inhibitor D, p19-INK4d, CDKN2D
Target/Specificity CDKN2D (AAH01822, 1 a.a. ~ 166 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCDKN2D Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.


Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis. Cunningham JM, et al. Br J Cancer, 2009 Oct 20. PMID 19738611.Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis. Zhang W, et al. Acta Biochim Biophys Sin (Shanghai), 2009 May. PMID 19430707.Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk. Goode EL, et al. Cancer Epidemiol Biomarkers Prev, 2009 Mar. PMID 19258477.Rare germline mutations in cyclin-dependent kinase inhibitor genes in multiple endocrine neoplasia type 1 and related states. Agarwal SK, et al. J Clin Endocrinol Metab, 2009 May. PMID 19141585.Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer. Mavaddat N, et al. Cancer Epidemiol Biomarkers Prev, 2009 Jan. PMID 19124506.

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$ 315.00
Cat# AT1483a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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