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>   home   >   Products   >   Primary Antibodies   >   CENPJ Antibody (monoclonal) (M01)   

CENPJ Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CENPJ.

  • WB - CENPJ Antibody (monoclonal) (M01) AT1494a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • IHC - CENPJ Antibody (monoclonal) (M01) AT1494a
    Immunoperoxidase of monoclonal antibody to CENPJ on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 1.5 ug/ml]
  • E - CENPJ Antibody (monoclonal) (M01) AT1494a
    Detection limit for recombinant GST tagged CENPJ is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9HC77
Other Accession NM_018451
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 5D5
Calculated MW 153000 Da
Additional Information
Gene ID 55835
Other Names Centromere protein J, CENP-J, Centrosomal P41-associated protein, LAG-3-associated protein, LYST-interacting protein 1, CENPJ, CPAP, LAP, LIP1
Target/Specificity CENPJ (NP_060921, 979 a.a. ~ 1088 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCENPJ Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.


PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle. Chang J, et al. EMBO J, 2010 Jul 21. PMID 20531387.Novel CENPJ mutation causes Seckel syndrome. Al-Dosari MS, et al. J Med Genet, 2010 Jun. PMID 20522431.Sex-dependent association of common variants of microcephaly genes with brain structure. Rimol LM, et al. Proc Natl Acad Sci U S A, 2010 Jan 5. PMID 20080800.Dimerization of CPAP orchestrates centrosome cohesion plasticity. Zhao L, et al. J Biol Chem, 2010 Jan 22. PMID 19889632.CPAP is a cell-cycle regulated protein that controls centriole length. Tang CJ, et al. Nat Cell Biol, 2009 Jul. PMID 19503075.

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$ 315.00
Cat# AT1494a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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