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CGGBP1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant CGGBP1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q9UFW8 |
| Other Accession | NM_003663 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1D11 |
| Calculated MW | 18820 Da |
| Gene ID | 8545 |
|---|---|
| Other Names | CGG triplet repeat-binding protein 1, CGG-binding protein 1, 20 kDa CGG-binding protein, p20-CGGBP DNA-binding protein, CGGBP1, CGGBP |
| Target/Specificity | CGGBP1 (NP_003654, 58 a.a. ~ 167 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | CGGBP1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.
References
[The role of ZF5 and CGGBP-20 transcription factors in expression regulation of human FMR1 gene responsible for X-fragile syndrome] Guly? PV, et al. Tsitologiia, 2009. PMID 20141036.Fragile X gene stability in Basque Valleys: prevalence of premutation and intermediate alleles. Arrieta I, et al. Hum Biol, 2008 Dec. PMID 19728537.The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.From ORFeome to biology: a functional genomics pipeline. Wiemann S, et al. Genome Res, 2004 Oct. PMID 15489336.
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