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CIAPIN1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant CIAPIN1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6FI81 |
| Other Accession | NM_020313 |
| Reactivity | Human, Mouse, Rat |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Lambda |
| Clone Names | 5G8 |
| Calculated MW | 33582 Da |
| Gene ID | 57019 |
|---|---|
| Other Names | Anamorsin {ECO:0000255|HAMAP-Rule:MF_03115}, Cytokine-induced apoptosis inhibitor 1 {ECO:0000255|HAMAP-Rule:MF_03115}, Fe-S cluster assembly protein DRE2 homolog {ECO:0000255|HAMAP-Rule:MF_03115}, CIAPIN1 {ECO:0000255|HAMAP-Rule:MF_03115} |
| Target/Specificity | CIAPIN1 (NP_064709, 266 a.a. ~ 367 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | CIAPIN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).
References
A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. Vernis L, et al. PLoS One, 2009. PMID 19194512.CIAPIN1 inhibits the growth and proliferation of clear cell renal cell carcinoma. He L, et al. Cancer Lett, 2009 Apr 8. PMID 19081179.Dre2, a conserved eukaryotic Fe/S cluster protein, functions in cytosolic Fe/S protein biogenesis. Zhang Y, et al. Mol Cell Biol, 2008 Sep. PMID 18625724.[Reversal of multidrug resistance of gastric cancer cells by down-regulation of CIAPIN1 with CIAPIN1 siRNA] Li X, et al. Mol Biol (Mosk), 2008 Jan-Feb. PMID 18389626.Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo. Li X, et al. Carcinogenesis, 2008 Aug. PMID 18299278.
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