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CIB1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant CIB1.

     
  • IF - CIB1 Antibody (monoclonal) (M01) AT1537a
    Immunofluorescence of monoclonal antibody to CIB1 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • WB - CIB1 Antibody (monoclonal) (M01) AT1537a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (46.75 KDa) .
    detail
  • IHC - CIB1 Antibody (monoclonal) (M01) AT1537a
    Immunoperoxidase of monoclonal antibody to CIB1 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF
Primary Accession Q99828
Other Accession BC000846
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4D2-3A8
Calculated MW 21703 Da
Additional Information
Gene ID 10519
Other Names Calcium and integrin-binding protein 1, CIB, Calcium- and integrin-binding protein, CIBP, Calmyrin, DNA-PKcs-interacting protein, Kinase-interacting protein, KIP, SNK-interacting protein 2-28, SIP2-28, CIB1, CIB, KIP, PRKDCIP
Target/Specificity CIB1 (AAH00846, 1 a.a. ~ 191 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCIB1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3).

References

Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1. Jarman KE, et al. J Biol Chem, 2010 Jan 1. PMID 19854831.Auxiliary Ca2+ binding sites can influence the structure of CIB1. Yamniuk AP, et al. Protein Sci, 2009 May. PMID 19388079.Characterization of calcium- and integrin-binding protein 1 (CIB1) knockout platelets: potential compensation by CIB family members. Denofrio JC, et al. Thromb Haemost, 2008 Nov. PMID 18989529.

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$ 350.00
Cat# AT1537a
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