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CITED4 Antibody (monoclonal) (M08)

Mouse monoclonal antibody raised against a partial recombinant CITED4.

     
  • IF - CITED4 Antibody (monoclonal) (M08) AT1542a
    Immunofluorescence of monoclonal antibody to CITED4 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • WB - CITED4 Antibody (monoclonal) (M08) AT1542a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.68 KDa) .
    detail
  • WB - CITED4 Antibody (monoclonal) (M08) AT1542a
    Western Blot analysis of CITED4 expression in transfected 293T cell line by CITED4 monoclonal antibody (M08), clone 4F6.

    Lane 1: CITED4 transfected lysate(18.6 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • IHC - CITED4 Antibody (monoclonal) (M08) AT1542a
    Immunoperoxidase of monoclonal antibody to CITED4 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF
Primary Accession Q96RK1
Other Accession NM_133467
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4F6
Calculated MW 18569 Da
Additional Information
Gene ID 163732
Other Names Cbp/p300-interacting transactivator 4, MSG1-related protein 2, MRG-2, CITED4 (HGNC:18696), MRG2
Target/Specificity CITED4 (NP_597724.1, 131 a.a. ~ 184 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCITED4 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

CITED4 belongs to a family of transcriptional coactivators that bind several proteins, including CREB-binding protein (MIM 600140) and p300 (MIM 602700).

References

Mutational analysis of the CITED4 gene in glioblastomas. Torres-Mart?n M, et al. Cancer Genet Cytogenet, 2008 Sep. PMID 18722883.Hypermethylation and transcriptional downregulation of the CITED4 gene at 1p34.2 in oligodendroglial tumours with allelic losses on 1p and 19q. Tews B, et al. Oncogene, 2007 Jul 26. PMID 17311001.Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and beta-catenin. Labalette C, et al. Mol Cell Biol, 2004 Dec. PMID 15572674.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha. Fox SB, et al. Cancer Res, 2004 Sep 1. PMID 15342390.

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$ 350.00
Cat# AT1542a
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Availability: 7-10 days
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