CNOT2 Antibody (monoclonal) (M08)Purified Mouse Monoclonal Antibody (Mab)

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Catalog #	Size	Availability	Price
AT1571a	50 ug 400 ul	7-10 days	$ 315.00	DISCONTINED INQUIRE CLICK INQUIRE Add to cart

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CNOT2 Antibody (monoclonal) (M08) - Product info
Application	WB Applications Legend: W=Western Blotting IP=Immunoprecipitation IHC-P=Immunohistochemistry (Paraffin) IF-IC=Immunofluorescence (Immunocytochemistry) F=Flow Cytometry
Primary Accession	Q9NZN8
Other Accession	NP_055330
Reactivity	Human
Isotype	IgG2a Kappa
Clone Names	3F1
Calculated MW	59738 Da
CNOT2 Antibody (monoclonal) (M08) - Additional info
Gene ID 4848
Other Names CDC36, HSPC131, NOT2, NOT2H CCR4-NOT transcription complex, subunit 2
Target/Specificity CNOT2 (NP_055330, 441 a.a. ~ 541 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions CNOT2 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.

CNOT2 Antibody (monoclonal) (M08) - Related products

RI11140: CNOT2 predesign siRNA

DC01022: Human CNOT2 cDNA Clone

AT1571a: CNOT2 Antibody (monoclonal) (M08)

CNOT2 Antibody (monoclonal) (M08) - Application data

CNOT2 monoclonal antibody (M08), clone 3F1 Western Blot analysis of CNOT2 expression in A-549 ( Cat # L025V1 ).

CNOT2 Antibody (monoclonal) (M08) - Research Areas

Antibodies Biological Process Metabolic Process Primary Metabolic Process Cellular Metabolic Process Cellular Process Macromolecule Metabolic Process Cellular Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Biological Regulation Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Biological Process Biosynthetic Process Cellular Biosynthetic Process Regulation Of Cellular Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Compartment Cytoplasm Nucleus Intracellular Part Intracellular Membrane-bounded Organelle Intracellular Membrane-bounded Organelle Organelle Intracellular Organelle Molecular Function Transcription Regulator Activity Protein Binding RNA Polymerase II Transcription Factor Activity Tissue Heart Kidney Lymph Skin

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REFERENCES

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex. Miyasaka T, et al. Cancer Sci, 2008 Apr. PMID 18377426.Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth. Morita M, et al. Mol Cell Biol, 2007 Jul. PMID 17452450.Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription. Winkler GS, et al. EMBO J, 2006 Jul 12. PMID 16778766.Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex. Jayne S, et al. Biochem J, 2006 Sep 15. PMID 16712523.