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COASY Antibody (monoclonal) (M05)

Mouse monoclonal antibody raised against a partial recombinant COASY.

  • WB - COASY Antibody (monoclonal) (M05) AT1577a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.18 KDa) .
  • IHC - COASY Antibody (monoclonal) (M05) AT1577a
    Immunoperoxidase of monoclonal antibody to COASY on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
  • E - COASY Antibody (monoclonal) (M05) AT1577a
    Detection limit for recombinant GST tagged COASY is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13057
Other Accession NM_025233
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2A12
Calculated MW 62329 Da
Additional Information
Gene ID 80347
Other Names Bifunctional coenzyme A synthase, CoA synthase, NBP, POV-2, Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT, Dephospho-CoA kinase, DPCK, Dephosphocoenzyme A kinase, DPCOAK, COASY
Target/Specificity COASY (NP_079509, 461 a.a. ~ 564 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCOASY Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC and dephospho-CoA kinase (DPCK; EC, in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]).


Genetic susceptibility to distinct bladder cancer subphenotypes. Guey LT, et al. Eur Urol, 2010 Feb. PMID 19692168.CoA synthase is in complex with p85alphaPI3K and affects PI3K signaling pathway. Breus O, et al. Biochem Biophys Res Commun, 2009 Aug 7. PMID 19482007.Possible difference in frequencies of genetic polymorphisms of estrogen receptor alpha, estrogen metabolism and P53 genes between estrogen receptor-positive and -negative breast cancers. Hamaguchi M, et al. Jpn J Clin Oncol, 2008 Nov. PMID 18820009.Identification of a novel CoA synthase isoform, which is primarily expressed in the brain. Nemazanyy I, et al. Biochem Biophys Res Commun, 2006 Mar 24. PMID 16460672.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.

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$ 315.00
Cat# AT1577a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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