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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CORIN Antibody (monoclonal) (M01)   

CORIN Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CORIN.

  • WB - CORIN Antibody (monoclonal) (M01) AT1593a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • E - CORIN Antibody (monoclonal) (M01) AT1593a
    Detection limit for recombinant GST tagged CORIN is approximately 3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y5Q5
Other Accession NM_006587
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 5B6
Calculated MW 116486 Da
Additional Information
Gene ID 10699
Other Names Atrial natriuretic peptide-converting enzyme, 3421-, Corin, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, Transmembrane protease serine 10, Atrial natriuretic peptide-converting enzyme, N-terminal propeptide, Atrial natriuretic peptide-converting enzyme, activated protease fragment, Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment, Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment, Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment, CORIN, CRN, TMPRSS10
Target/Specificity CORIN (NP_006578, 616 a.a. ~ 715 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCORIN Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Dysfunctional corin i555(p568) allele is associated with impaired brain natriuretic peptide processing and adverse outcomes in blacks with systolic heart failure: results from the Genetic Risk Assessment in Heart Failure substudy. Rame JE, et al. Circ Heart Fail, 2009 Nov. PMID 19919978.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting. Fox AA, et al. Anesthesiology, 2009 Apr. PMID 19326473.Corin variant associated with hypertension and cardiac hypertrophy exhibits impaired zymogen activation and natriuretic peptide processing activity. Wang W, et al. Circ Res, 2008 Aug 29. PMID 18669922.

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$ 315.00
Cat# AT1593a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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