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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   COX17 Antibody (monoclonal) (M01)   

COX17 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant COX17.

  • WB - COX17 Antibody (monoclonal) (M01) AT1597a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.67 KDa) .
  • WB - COX17 Antibody (monoclonal) (M01) AT1597a
    COX17 monoclonal antibody (M01), clone 4G2. Western Blot analysis of COX17 expression in IMR-32.
  • IHC - COX17 Antibody (monoclonal) (M01) AT1597a
    Immunoperoxidase of monoclonal antibody to COX17 on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml]
  • E - COX17 Antibody (monoclonal) (M01) AT1597a
    Detection limit for recombinant GST tagged COX17 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14061
Other Accession NM_005694
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 4G2
Calculated MW 6915 Da
Additional Information
Gene ID 10063
Other Names Cytochrome c oxidase copper chaperone, COX17
Target/Specificity COX17 (NP_005685, 1 a.a. ~ 63 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCOX17 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.


1.Dysregulation of intracellular copper homeostasis is common to transgenic mice expressing human mutant superoxide dismutase-1s regardless of their copper-binding abilities.Tokuda E, Okawa E, Watanabe S, Ono SI, Marklund SL.Neurobiol Dis. 2013 Jan 13. doi:pii: S0969-9961(13)00013-2. 10.1016/j.nbd.2013.01.001. [Epub ahead of print]

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$ 315.00
Cat# AT1597a
(40 western blots)
Availability: 7-10 days
Bulk Size
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