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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CRADD Antibody (monoclonal) (M01)   

CRADD Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant CRADD.

  • WB - CRADD Antibody (monoclonal) (M01) AT1616a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (47.63 KDa) .
  • WB - CRADD Antibody (monoclonal) (M01) AT1616a
    CRADD monoclonal antibody (M01), clone 1F8 Western Blot analysis of CRADD expression in K-562 ( (Cat # AT1616a )
  • WB - CRADD Antibody (monoclonal) (M01) AT1616a
    Western Blot analysis of CRADD expression in transfected 293T cell line by CRADD monoclonal antibody (M01), clone 1F8.

    Lane 1: CRADD transfected lysate(23 KDa).
    Lane 2: Non-transfected lysate.
  • IF - CRADD Antibody (monoclonal) (M01) AT1616a
    Immunofluorescence of monoclonal antibody to CRADD on HeLa cell. [antibody concentration 10 ug/ml]
  • E - CRADD Antibody (monoclonal) (M01) AT1616a
    Detection limit for recombinant GST tagged CRADD is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78560
Other Accession BC037905
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 1F8
Calculated MW 22745 Da
Additional Information
Gene ID 8738
Other Names Death domain-containing protein CRADD, Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD, RAIDD
Target/Specificity CRADD (AAH37905, 1 a.a. ~ 199 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCRADD Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.


An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. Zhao J, et al. BMC Med Genet, 2010 Jun 14. PMID 20546612.Identification and analysis of dominant negative mutants of RAIDD and PIDD. Jang TH, et al. Biochim Biophys Acta, 2010 Jul. PMID 20406701.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.PIDDosome expression and the role of caspase-2 activation for chemotherapy-induced apoptosis in RCCs. Heikaus S, et al. Cell Oncol, 2010. PMID 20208132.

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$ 315.00
Cat# AT1616a
(40 western blots)
Availability: 7-10 days
Bulk Size
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