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CREB3 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CREB3.

  • WB - CREB3 Antibody (monoclonal) (M01) AT1617a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - CREB3 Antibody (monoclonal) (M01) AT1617a
    Western Blot analysis of CREB3 expression in transfected 293T cell line by CREB3 monoclonal antibody (M01), clone 3H5.

    Lane 1: CREB3 transfected lysate(41.4 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - CREB3 Antibody (monoclonal) (M01) AT1617a
    Immunoperoxidase of monoclonal antibody to CREB3 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
  • E - CREB3 Antibody (monoclonal) (M01) AT1617a
    Detection limit for recombinant GST tagged CREB3 is approximately 0.1ng/ml as a capture antibody.
  • WB - CREB3 Antibody (monoclonal) (M01) AT1617a
    Western blot analysis of CREB3 over-expressed 293 cell line, cotransfected with CREB3 Validated Chimera RNAi ( (Cat # AT1617a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43889
Other Accession NM_006368
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3H5
Calculated MW 43917 Da
Additional Information
Gene ID 10488
Other Names Cyclic AMP-responsive element-binding protein 3, CREB-3, cAMP-responsive element-binding protein 3, Leucine zipper protein, Luman, Transcription factor LZIP-alpha, Processed cyclic AMP-responsive element-binding protein 3, N-terminal Luman, Transcriptionally active form, CREB3, LZIP
Target/Specificity CREB3 (NP_006359, 273 a.a. ~ 371 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCREB3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.


DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation. Eleveld-Trancikova D, et al. Mol Immunol, 2010 Jul. PMID 20546900.A novel isoform of human LZIP negatively regulates the transactivation of the glucocorticoid receptor. Kang H, et al. Mol Endocrinol, 2009 Nov. PMID 19779205.A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response. Audas TE, et al. Mol Cell Biol, 2008 Jun. PMID 18391022.Lithium response and genetic variation in the CREB family of genes. Mamdani F, et al. Am J Med Genet B Neuropsychiatr Genet, 2008 Jun 5. PMID 18189280.Regulation of human LZIP expression by NF-kappaB and its involvement in monocyte cell migration induced by Lkn-1. Jang SW, et al. J Biol Chem, 2007 Apr 13. PMID 17296613.

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$ 315.00
Cat# AT1617a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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