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CTBP1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant CTBP1.
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q13363 |
| Other Accession | BC053320 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b kappa |
| Clone Names | 2G7 |
| Calculated MW | 47535 Da |
| Gene ID | 1487 |
|---|---|
| Other Names | C-terminal-binding protein 1, CtBP1, 111-, CTBP1, CTBP |
| Target/Specificity | CTBP1 (AAH53320, 1 a.a. ~ 429 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | CTBP1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
References
Inhibition of CtBP1 activity by Akt-mediated phosphorylation. Merrill JC, et al. J Mol Biol, 2010 May 21. PMID 20361981.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Association of genetic variants with hemorrhagic stroke in Japanese individuals. Yoshida T, et al. Int J Mol Med, 2010 Apr. PMID 20198315.Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. Oguri M, et al. Am J Hypertens, 2010 Jan. PMID 19851296.Ligand-dependent corepressor LCoR is an attenuator of progesterone-regulated gene expression. Palijan A, et al. J Biol Chem, 2009 Oct 30. PMID 19744932.
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