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DCTD Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant DCTD.

  • WB - DCTD Antibody (monoclonal) (M01) AT1721a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - DCTD Antibody (monoclonal) (M01) AT1721a
    Western Blot analysis of DCTD expression in transfected 293T cell line by DCTD monoclonal antibody (M01), clone 4B9.

    Lane 1: DCTD transfected lysate(20.016 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - DCTD Antibody (monoclonal) (M01) AT1721a
    Immunoperoxidase of monoclonal antibody to DCTD on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
  • E - DCTD Antibody (monoclonal) (M01) AT1721a
    Detection limit for recombinant GST tagged DCTD is 0.03 ng/ml as a capture antibody.
  • WB - DCTD Antibody (monoclonal) (M01) AT1721a
    Western blot analysis of DCTD over-expressed 293 cell line, cotransfected with DCTD Validated Chimera RNAi ( (Cat # AT1721a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32321
Other Accession NM_001921.2
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG3 Kappa
Clone Names 4B9
Calculated MW 20016 Da
Additional Information
Gene ID 1635
Other Names Deoxycytidylate deaminase, dCMP deaminase, DCTD
Target/Specificity DCTD (NP_001912.2, 69 a.a. ~ 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsDCTD Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.


Gemcitabine metabolic and transporter gene polymorphisms are associated with drug toxicity and efficacy in patients with locally advanced pancreatic cancer. Tanaka M, et al. Cancer, 2010 Jul 21. PMID 20665488.Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity. Okazaki T, et al. Clin Cancer Res, 2010 Jan 1. PMID 20028759.An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients. Rha SY, et al. Oncologist, 2007 Jun. PMID 17602053.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Rush J, et al. Nat Biotechnol, 2005 Jan. PMID 15592455.

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$ 315.00
Cat# AT1721a
(40 western blots)
Availability: 7-10 days
Bulk Size
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