DCUN1D1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant DCUN1D1.
|Reactivity||Human, Mouse, Rat|
|Calculated MW||30124 Da|
|Other Names||DCN1-like protein 1, DCUN1 domain-containing protein 1, Defective in cullin neddylation protein 1-like protein 1, Squamous cell carcinoma-related oncogene, DCUN1D1, DCUN1L1, RP42, SCCRO|
|Target/Specificity||DCUN1D1 (NP_065691, 1 a.a. ~ 89 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||DCUN1D1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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DCUN1D1 is a risk factor for frontotemporal lobar degeneration. Villa C, et al. Eur J Neurol, 2009 Jul. PMID 19473369.SCCRO (DCUN1D1) induces extracellular matrix invasion by activating matrix metalloproteinase 2. O-charoenrat P, et al. Clin Cancer Res, 2008 Nov 1. PMID 18980971.SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation. Kim AY, et al. J Biol Chem, 2008 Nov 28. PMID 18826954.Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas. Sarkaria I, et al. Cancer Res, 2006 Oct 1. PMID 17018598.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.
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