DEF6 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant DEF6.
|Application ||WB, IHC, IP, E|
|Calculated MW||73910 Da|
|Other Names||Differentially expressed in FDCP 6 homolog, DEF-6, IRF4-binding protein, DEF6, IBP|
|Target/Specificity||DEF6 (AAH17504, 1 a.a. ~ 336 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||DEF6 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM]
1.Def-6, a Novel Regulator of Small GTPases in Podocytes, Acts Downstream of Atypical Protein Kinase C (aPKC) ?/?.Worthmann K, Leitges M, Teng B, Sestu M, Tossidou I, Samson T, Haller H, Huber TB, Schiffer MAm J Pathol. 2013 Oct 3. pii: S0002-9440(13)00614-7. doi: 10.1016/j.ajpath.2013.08.026.
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