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DEFB4 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant DEFB4.

  • WB - DEFB4 Antibody (monoclonal) (M01) AT1751a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (30.25 KDa) .
  • WB - DEFB4 Antibody (monoclonal) (M01) AT1751a
    Western Blot analysis of DEFB4 expression in transfected 293T cell line by DEFB4 monoclonal antibody (M01), clone 4C4.

    Lane 1: DEFB4 transfected lysate(7.038 KDa).
    Lane 2: Non-transfected lysate.
  • E - DEFB4 Antibody (monoclonal) (M01) AT1751a
    Detection limit for recombinant GST tagged DEFB4 is approximately 3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15263
Other Accession NM_004942
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4C4
Calculated MW 7038 Da
Additional Information
Gene ID 100289462;1673
Other Names Beta-defensin 4A, Beta-defensin 2, BD-2, hBD-2, Defensin, beta 2, Skin-antimicrobial peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4
Target/Specificity DEFB4 (NP_004933, 24 a.a. ~ 64 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsDEFB4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.


Polymorphisms of Beta Defensins Are Associated with the Risk of Severe Acute Pancreatitis. Tiszlavicz Z, et al. Pancreatology, 2010 Aug 19. PMID 20720450.Differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria. Yin L, et al. BMC Immunol, 2010 Jul 9. PMID 20618959.Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2. R?hrl J, et al. J Immunol, 2010 Jun 15. PMID 20483750.Genomic copy number determines functional expression of {beta}-defensin 2 in airway epithelial cells and associates with chronic obstructive pulmonary disease. Janssens W, et al. Am J Respir Crit Care Med, 2010 Jul 15. PMID 20378733.Bacteroides fragilis enterotoxin induces human beta-defensin-2 expression in intestinal epithelial cells via a mitogen-activated protein kinase/I kappaB kinase/NF-kappaB-dependent pathway. Yoon YM, et al. Infect Immun, 2010 May. PMID 20231411.

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$ 315.00
Cat# AT1751a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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