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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DHODH Antibody (monoclonal) (M01)   

DHODH Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant DHODH.

  • WB - DHODH Antibody (monoclonal) (M01) AT1759a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) .
  • WB - DHODH Antibody (monoclonal) (M01) AT1759a
    DHODH monoclonal antibody (M01), clone 6E1 Western Blot analysis of DHODH expression in MCF-7 ( (Cat # AT1759a )
  • IHC - DHODH Antibody (monoclonal) (M01) AT1759a
    Immunoperoxidase of monoclonal antibody to DHODH on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml]
  • E - DHODH Antibody (monoclonal) (M01) AT1759a
    Detection limit for recombinant GST tagged DHODH is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02127
Other Accession NM_001361
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Lambda
Clone Names 60
Calculated MW 42867 Da
Additional Information
Gene ID 1723
Other Names Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase, DHODH
Target/Specificity DHODH (NP_001352, 32 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsDHODH Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.


Exome sequencing identifies the cause of a mendelian disorder. Ng SB, et al. Nat Genet, 2010 Jan. PMID 19915526.Dihydroorotate dehydrogenase polymorphism influences the toxicity of leflunomide treatment in patients with rheumatoid arthritis. Grabar PB, et al. Ann Rheum Dis, 2009 Aug. PMID 19605743.The effect of exon (19C>A) dihydroorotate dehydrogenase gene polymorphism on rheumatoid arthritis treatment with leflunomide. Pawlik A, et al. Pharmacogenomics, 2009 Feb. PMID 19207032.Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. Anney RJ, et al. Am J Med Genet B Neuropsychiatr Genet, 2008 Dec 5. PMID 18951430.The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites. Walse B, et al. Biochemistry, 2008 Aug 26. PMID 18672895.

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$ 315.00
Cat# AT1759a
(40 western blots)
Availability: 7-10 days
Bulk Size
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