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DKK1 Antibody (monoclonal) (M11)

Mouse monoclonal antibody raised against a full length recombinant DKK1.

  • WB - DKK1 Antibody (monoclonal) (M11) AT1769a
    DKK1 monoclonal antibody (M11), clone 2A5 Western Blot analysis of DKK1 expression in U-2 OS ( Cat # L022V1 ).
  • IHC - DKK1 Antibody (monoclonal) (M11) AT1769a
    Immunoperoxidase of monoclonal antibody to DKK1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
  • IP - DKK1 Antibody (monoclonal) (M11) AT1769a
    Immunoprecipitation of DKK1 transfected lysate using anti-DKK1 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with DKK1 MaxPab rabbit polyclonal antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94907
Other Accession BC001539
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 2A5
Calculated MW 28672 Da
Additional Information
Gene ID 22943
Other Names Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK, DKK1
Target/Specificity DKK1 (AAH01539.1, 1 a.a. ~ 266 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsDKK1 Antibody (monoclonal) (M11) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.


1.Genetic grouping of medulloblastomas by representative markers in pathologic diagnosis.Min HS, Lee JY, Kim SK, Park SHTransl Oncol. 2013 Jun 1;6(3):265-72. Print 2013 Jun.2.RNA interference?mediated targeting of DKK1 gene expression in Ishikawa endometrial carcinoma cells causes increased tumor cell invasion and migration.Yi N, Liao QP, Li ZH, Xie BJ, Hu YH, Yi W, Liu M.ONCOLOGY LETTERS 6: 756-762, 20133.Molecular subgroups of medulloblastoma: the current consensus.Taylor MD, Northcott PA, Korshunov A, Remke M, Cho YJ, Clifford SC, Eberhart CG, Parsons DW, Rutkowski S, Gajjar A, Ellison DW, Lichter P, Gilbertson RJ, Pomeroy SL, Kool M, Pfister SM.Acta Neuropathol. 2011 Dec 2.4.Prokineticin 1 induces Dickkopf 1 expression and regulates cell proliferation and decidualization in the human endometrium.Macdonald LJ, Sales KJ, Grant V, Brown P, Jabbour HN, Catalano RD.Mol Hum Reprod. 2011 May 5. [Epub ahead of print]5.Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion.Shin HJ, Rho SB, Jung DC, Han IO, Oh ES, Kim JY.J Cell Sci. 2011 Apr 1;124(Pt 7):1077-87. Epub 2011 Mar 1.6.Bone and bone marrow pro-osteoclastogenic cytokines are up-regulated in osteoporosis fragility fractures.D'Amelio P, Roato I, D'Amico L, Veneziano L, Suman E, Sassi F, Bisignano G, Ferracini R, Gargiulo G, Castoldi F, Pescarmona GP, Isaia GC.Osteoporos Int. 2010 Nov 30. [Epub ahead of print]

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$ 315.00
Cat# AT1769a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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