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DLX5 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant DLX5.

     
  • IF - DLX5 Antibody (monoclonal) (M01) AT1781a
    Immunofluorescence of monoclonal antibody to DLX5 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • E - DLX5 Antibody (monoclonal) (M01) AT1781a
    Detection limit for recombinant GST tagged DLX5 is approximately 0.3ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IF, E
Primary Accession P56178
Other Accession NM_005221
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1B3
Calculated MW 31540 Da
Additional Information
Gene ID 1749
Other Names Homeobox protein DLX-5, DLX5
Target/Specificity DLX5 (NP_005212, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsDLX5 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.

References

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.DLX5 (distal-less homeobox 5) promotes tumor cell proliferation by transcriptionally regulating MYC. Xu J, et al. J Biol Chem, 2009 Jul 31. PMID 19497851.High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Yerges LM, et al. J Bone Miner Res, 2009 Dec. PMID 19453261.Expression analysis and mutation detection of DLX5 and DLX6 in autism. Nakashima N, et al. Brain Dev, 2010 Feb. PMID 19195802.Activation of placenta-specific transcription factor distal-less homeobox 5 predicts clinical outcome in primary lung cancer patients. Kato T, et al. Clin Cancer Res, 2008 Apr 15. PMID 18413826.

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$ 350.00
Cat# AT1781a
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Availability: 7-10 days
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