DLX5 Antibody (monoclonal) (M07)
Mouse monoclonal antibody raised against a partial recombinant DLX5.
|Application ||IF, E|
|Calculated MW||31540 Da|
|Other Names||Homeobox protein DLX-5, DLX5|
|Target/Specificity||DLX5 (NP_005212, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||DLX5 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.DLX5 (distal-less homeobox 5) promotes tumor cell proliferation by transcriptionally regulating MYC. Xu J, et al. J Biol Chem, 2009 Jul 31. PMID 19497851.High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Yerges LM, et al. J Bone Miner Res, 2009 Dec. PMID 19453261.Expression analysis and mutation detection of DLX5 and DLX6 in autism. Nakashima N, et al. Brain Dev, 2010 Feb. PMID 19195802.Activation of placenta-specific transcription factor distal-less homeobox 5 predicts clinical outcome in primary lung cancer patients. Kato T, et al. Clin Cancer Res, 2008 Apr 15. PMID 18413826.
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