DNAJC10 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant DNAJC10.
|Reactivity||Human, Mouse, Rat|
|Calculated MW||91080 Da|
|Other Names||DnaJ homolog subfamily C member 10, 184-, Endoplasmic reticulum DNA J domain-containing protein 5, ER-resident protein ERdj5, ERdj5, Macrothioredoxin, MTHr, DNAJC10, ERDJ5|
|Target/Specificity||DNAJC10 (NP_061854, 688 a.a. ~ 793 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||DNAJC10 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C. Wang M, et al. J Biol Chem, 2009 Nov 27. PMID 19815549.ERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosis. Thomas CG, et al. J Biol Chem, 2009 Mar 6. PMID 19122239.ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. Ushioda R, et al. Science, 2008 Jul 25. PMID 18653895.ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Dong M, et al. Mol Biol Cell, 2008 Jun. PMID 18400946.Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. Otsuki T, et al. DNA Res, 2005. PMID 16303743.
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