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DNASE1L1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a full length recombinant DNASE1L1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P49184 |
| Other Accession | BC001561 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 4E9 |
| Calculated MW | 33893 Da |
| Gene ID | 1774 |
|---|---|
| Other Names | Deoxyribonuclease-1-like 1, 3121-, DNase X, Deoxyribonuclease I-like 1, DNase I-like 1, Muscle-specific DNase I-like, XIB, DNASE1L1, DNAS1L1, DNL1L |
| Target/Specificity | DNASE1L1 (AAH01561, 18 a.a. ~ 302 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DNASE1L1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
References
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Genetic and expression analysis of all non-synonymous single nucleotide polymorphisms in the human deoxyribonuclease I-like 1 and 2 genes. Ueki M, et al. Electrophoresis, 2010 Jun. PMID 20503202.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Isolation, differential splicing and protein expression of a DNase on the human X chromosome. Coy JF, et al. Cell Death Differ, 1996 Apr. PMID 17180083.The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901.
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