DNMBP Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant DNMBP.
|Calculated MW||177347 Da|
|Other Names||Dynamin-binding protein, Scaffold protein Tuba, DNMBP, KIAA1010|
|Target/Specificity||DNMBP (AAH41628, 491 a.a. ~ 590 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||DNMBP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
DNMBP belongs to the DBL (MIM 311030) family of guanine nucleotide exchange factors and plays a role in the regulation of cell junctions (Otani et al., 2006 [PubMed 17015620]).
Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. Voss M, et al. BMC Immunol, 2009 Oct 6. PMID 19807924.Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. Thalappilly S, et al. Proteomics, 2008 Aug. PMID 18654987.Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. Morgan AR, et al. Am J Med Genet B Neuropsychiatr Genet, 2009 Jan 5. PMID 18452187.DNMBP is genetically associated with Alzheimer dementia in the Belgian population. Bettens K, et al. Neurobiol Aging, 2009 Dec. PMID 18359537.No association of dynamin binding protein (DNMBP) gene SNPs and Alzheimer's disease. Minster RL, et al. Neurobiol Aging, 2008 Oct. PMID 17442457.
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