DUB3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant DUB3.
|Application ||WB, E|
|Calculated MW||59619 Da|
|Other Names||Ubiquitin carboxyl-terminal hydrolase 17, USP17, Deubiquitinating enzyme 17-like protein 2, Deubiquitinating protein 3, DUB-3, Ubiquitin carboxyl-terminal hydrolase 17-like protein 2, Ubiquitin thioesterase 17-like protein 2, Ubiquitin-specific-processing protease 17-like protein 2, USP17L2|
|Target/Specificity||DUB3 (NP_958804, 431 a.a. ~ 530 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||DUB3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for background information.
Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A. Pereg Y, et al. Nat Cell Biol, 2010 Apr. PMID 20228808.Personalized copy number and segmental duplication maps using next-generation sequencing. Alkan C, et al. Nat Genet, 2009 Oct. PMID 19718026.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation. Burrows JF, et al. J Biol Chem, 2004 Apr 2. PMID 14699124.
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