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EBI3 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant EBI3. (Please notice that this antibo

  • E - EBI3 Antibody (monoclonal) (M01) AT1847a
    Detection limit for recombinant GST tagged EBI3 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14213
Other Accession NM_005755
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1D3
Calculated MW 25396 Da
Additional Information
Gene ID 10148
Other Names Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein, EBV-induced gene 3 protein, EBI3, IL27B
Target/Specificity EBI3 (NP_005746, 129 a.a. ~ 229 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsEBI3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.


Epstein-barr virus-induced gene-3 is expressed in human atheroma plaques. Kempe S, et al. Am J Pathol, 2009 Jul. PMID 19556516.IL27: its roles in the induction and inhibition of inflammation. Carl JW, et al. Int J Clin Exp Pathol, 2008 Jan 1. PMID 18784808.Genome-wide analysis displays marked induction of EBI3/IL-27B in IL-18-activated AML-derived KG1 cells: critical role of two kappaB binding sites in the human EBI3 promotor. Poleganov MA, et al. Mol Immunol, 2008 May. PMID 18336908.Enhanced expression of IL-27 mRNA in human newborns. Krumbiegel D, et al. Pediatr Allergy Immunol, 2008 Sep. PMID 18167155.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.

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$ 315.00
Cat# AT1847a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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