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EDN1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant EDN1.

  • WB - EDN1 Antibody (monoclonal) (M01) AT1850a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - EDN1 Antibody (monoclonal) (M01) AT1850a
    Western Blot analysis of EDN1 expression in transfected 293T cell line by EDN1 monoclonal antibody (M01), clone 3D6.

    Lane 1: EDN1 transfected lysate(24 KDa).
    Lane 2: Non-transfected lysate.
  • IP - EDN1 Antibody (monoclonal) (M01) AT1850a
    Immunoprecipitation of EDN1 transfected lysate using anti-EDN1 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with EDN1 MaxPab rabbit polyclonal antibody.
  • E - EDN1 Antibody (monoclonal) (M01) AT1850a
    Detection limit for recombinant GST tagged EDN1 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05305
Other Accession BC009720
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a kappa
Clone Names 3D6
Calculated MW 24425 Da
Additional Information
Gene ID 1906
Other Names Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1
Target/Specificity EDN1 (AAH09720, 113 a.a. ~ 212 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsEDN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.


1.Calpain-6 is an endothelin-1 signaling dependent protective factor in chemoresistant osteosarcoma.Marion A, Dieudonne FX, Patino-Garcia A, Lecanda F, Marie PJ, Modrowski D.Int J Cancer. 2012 Jun 1;130(11):2514-25. doi: 10.1002/ijc.26246. Epub 2011 Aug 16.2.Endothelin type A and B receptors in the control of afferent and efferent arterioles in mice.Schildroth J, Rettig-Zimmermann J, Kalk P, Steege A, Fahling M, Sendeski M, Paliege A, Lai EY, Bachmann S, Persson PB, Hocher B, Patzak A.Nephrol Dial Transplant. 2010 Sep 2. [Epub ahead of print]3.Epithelial-to-Mesenchymal Transition and Resistance to Ingenol 3-Angelate, a Novel Protein Kinase C Modulator, in Colon Cancer Cells.Ghoul A, Serova M, Astorgues-Xerri L, Bieche I, Bousquet G, Varna M, Vidaud M, Phillips E, Weill S, Benhadji KA, Lokiec F, Cvitkovic E, Faivre S, Raymond E.Cancer Res. 2009 May 15;69(10):4260-9. Epub 2009 May 5.

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$ 315.00
Cat# AT1850a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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