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ELAVL1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant ELAVL1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q15717 |
| Other Accession | BC003376 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 4G8 |
| Calculated MW | 36092 Da |
| Gene ID | 1994 |
|---|---|
| Other Names | ELAV-like protein 1, Hu-antigen R, HuR, ELAVL1, HUR |
| Target/Specificity | ELAVL1 (AAH03376, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ELAVL1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
References
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.HuR regulates beta-tubulin isotype expression in ovarian cancer. Raspaglio G, et al. Cancer Res, 2010 Jul 15. PMID 20587520.The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro. Ahn J, et al. Retrovirology, 2010 May 7. PMID 20459669.Novel function and intracellular localization of methionine adenosyltransferase 2beta splicing variants. Xia M, et al. J Biol Chem, 2010 Jun 25. PMID 20421296.The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer. Calaluce R, et al. BMC Cancer, 2010 Apr 6. PMID 20370918.
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