ELAVL1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant ELAVL1.
|Application ||WB, IHC, IF, E|
|Calculated MW||36092 Da|
|Other Names||ELAV-like protein 1, Hu-antigen R, HuR, ELAVL1, HUR|
|Target/Specificity||ELAVL1 (AAH03376, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||ELAVL1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.HuR regulates beta-tubulin isotype expression in ovarian cancer. Raspaglio G, et al. Cancer Res, 2010 Jul 15. PMID 20587520.The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro. Ahn J, et al. Retrovirology, 2010 May 7. PMID 20459669.Novel function and intracellular localization of methionine adenosyltransferase 2beta splicing variants. Xia M, et al. J Biol Chem, 2010 Jun 25. PMID 20421296.The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer. Calaluce R, et al. BMC Cancer, 2010 Apr 6. PMID 20370918.
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