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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ENG Antibody (monoclonal) (M01)   

ENG Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant ENG.

  • WB - ENG Antibody (monoclonal) (M01) AT1907a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (95.26 KDa) .
  • WB - ENG Antibody (monoclonal) (M01) AT1907a
    Western Blot analysis of ENG expression in transfected 293T cell line by ENG monoclonal antibody (M01), clone 4C11.

    Lane 1: ENG transfected lysate(70.6 KDa).
    Lane 2: Non-transfected lysate.
  • IP - ENG Antibody (monoclonal) (M01) AT1907a
    Immunoprecipitation of ENG transfected lysate using anti-ENG monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with ENG MaxPab rabbit polyclonal antibody.
  • E - ENG Antibody (monoclonal) (M01) AT1907a
    Detection limit for recombinant GST tagged ENG is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17813
Other Accession BC014271
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4C11
Calculated MW 70578 Da
Additional Information
Gene ID 2022
Other Names Endoglin, CD105, ENG, END
Target/Specificity ENG (AAH14271, 27 a.a. ~ 658 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsENG Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Soluble endoglin in preeclamptic patients with or without HELLP syndrome. Hertig A, et al. Am J Obstet Gynecol, 2010 Jun. PMID 20430360.Update on molecular diagnosis of hereditary hemorrhagic telangiectasia. Richards-Yutz J, et al. Hum Genet, 2010 Jul. PMID 20414677.Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. Roberts KE, et al. Gastroenterology, 2010 Jul. PMID 20346360.Alterations of serum and placental endoglin in pre-eclampsia. Fang M, et al. J Int Med Res, 2010 Jan-Feb. PMID 20233512.

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$ 315.00
Cat# AT1907a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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