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EPB41 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant EPB41.

  • WB - EPB41 Antibody (monoclonal) (M01) AT1922a
    Western Blot analysis of EPB41 expression in transfected 293T cell line by EPB41 monoclonal antibody (M01), clone 3D9.

    Lane 1: EPB41 transfected lysate(81 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - EPB41 Antibody (monoclonal) (M01) AT1922a
    Immunoperoxidase of monoclonal antibody to EPB41 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]
  • IF - EPB41 Antibody (monoclonal) (M01) AT1922a
    Immunofluorescence of monoclonal antibody to EPB41 on HeLa cell . [antibody concentration 10 ug/ml]
  • E - EPB41 Antibody (monoclonal) (M01) AT1922a
    Detection limit for recombinant GST tagged EPB41 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11171
Other Accession BC039079
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 3D9
Calculated MW 97017 Da
Additional Information
Gene ID 2035
Other Names Protein 41, P41, 41R, Band 41, EPB41, EPB41, E41P
Target/Specificity EPB41 (AAH39079, 116 a.a. ~ 225 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsEPB41 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.


Identification of SNP markers on 1p36 and association analysis of EPB41 with mandibular prognathism in a Chinese population. Xue F, et al. Arch Oral Biol, 2010 Aug 24. PMID 20797695.Protein 4.2 binds to the carboxyl-terminal EF-hands of erythroid alpha-spectrin in a calcium- and calmodulin-dependent manner. Korsgren C, et al. J Biol Chem, 2010 Feb 12. PMID 20007969.Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene. Huang SC, et al. Blood, 2009 Nov 5. PMID 19729518.Solution structure and glycophorin C binding studies of the protein 4.1R FERM alpha-lobe domain. Kusunoki H, et al. Proteins, 2009 Jul. PMID 19338061.Alternatively spliced exon 5 of the FERM domain of protein 4.1R encodes a novel binding site for erythrocyte p55 and is critical for membrane targeting in epithelial cells. Seo PS, et al. Biochim Biophys Acta, 2009 Feb. PMID 18952129.

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$ 315.00
Cat# AT1922a
(40 western blots)
Availability: 7-10 days
Bulk Size
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