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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   EPOR Antibody (monoclonal) (M02)   

EPOR Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant EPOR.

  • WB - EPOR Antibody (monoclonal) (M02) AT1932a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - EPOR Antibody (monoclonal) (M02) AT1932a
    EPOR monoclonal antibody (M02), clone 3F6. Western Blot analysis of EPOR expression in HeLa ( (Cat # AT1932a )
  • WB - EPOR Antibody (monoclonal) (M02) AT1932a
    Western Blot analysis of EPOR expression in transfected 293T cell line by EPOR monoclonal antibody (M02), clone 3F6.

    Lane 1: EPOR transfected lysate (Predicted MW: 55.1 KDa).
    Lane 2: Non-transfected lysate.
  • E - EPOR Antibody (monoclonal) (M02) AT1932a
    Detection limit for recombinant GST tagged EPOR is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P19235
Other Accession NM_000121
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 3F6
Calculated MW 55065 Da
Additional Information
Gene ID 2057
Other Names Erythropoietin receptor, EPO-R, EPOR
Target/Specificity EPOR (NP_000112, 31 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsEPOR Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.


A diversity of antibody epitopes can induce signaling through the erythropoietin receptor. Lim AC, et al. Biochemistry, 2010 May 11. PMID 20337434.STAT3 and hypoxia induced proteins--HIF-1alpha, EPO and EPOR in relation with Bax and Bcl-xL in nodal metastases of ductal breast cancers. Wincewicz A, et al. Folia Histochem Cytobiol, 2009 Jan. PMID 20164027.Absence of functional EpoR expression in human tumor cell lines. Swift S, et al. Blood, 2010 May 27. PMID 20124514.Functional erythropoietin receptor is undetectable in endothelial, cardiac, neuronal, and renal cells. Sinclair AM, et al. Blood, 2010 May 27. PMID 20124513.Induction of nitric oxide by erythropoietin is mediated by the {beta} common receptor and requires interaction with VEGF receptor 2. Sautina L, et al. Blood, 2010 Jan 28. PMID 19965681.

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$ 315.00
Cat# AT1932a
(40 western blots)
Availability: 7-10 days
Bulk Size
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