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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ERN1 Antibody (monoclonal) (M06)   

ERN1 Antibody (monoclonal) (M06)

Mouse monoclonal antibody raised against a partial recombinant ERN1.

  • WB - ERN1 Antibody (monoclonal) (M06) AT1945a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - ERN1 Antibody (monoclonal) (M06) AT1945a
    ERN1 monoclonal antibody (M06), clone 3D1 Western Blot analysis of ERN1 expression in HeLa ( (Cat # AT1945a )
  • IHC - ERN1 Antibody (monoclonal) (M06) AT1945a
    Immunoperoxidase of monoclonal antibody to ERN1 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 1.5 ug/ml]
  • E - ERN1 Antibody (monoclonal) (M06) AT1945a
    Detection limit for recombinant GST tagged ERN1 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75460
Other Accession AF059198
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 3D1
Calculated MW 109735 Da
Additional Information
Gene ID 2081
Other Names Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, hIRE1p, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, 3126-, ERN1 (HGNC:3449)
Target/Specificity ERN1 (AAC25991, 401 a.a. ~ 500 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsERN1 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations ( 0 )


The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells. Qiu Y, et al. Sci Signal, 2010 Jan 26. PMID 20103773.NR2F1 and IRE1beta suppress microsomal triglyceride transfer protein expression and lipoprotein assembly in undifferentiated intestinal epithelial cells. Dai K, et al. Arterioscler Thromb Vasc Biol, 2010 Mar. PMID 20007910.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.

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$ 315.00
Cat# AT1945a
(40 western blots)
Availability: 7-10 days
Bulk Size
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